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  • 陈炯

教授,医药生物技术国家重点实验室 

地址:南京市栖霞区仙林大道163号,210023

邮箱:chenjiong@nju.edu.cn










研究领域


组织和器官形成,细胞迁移,细胞骨架,机械力传导




工作经历


2006-,南京大学博士生导师

2006-,南京大学教授



学术任职


中国细胞生物学会细胞结构与细胞行为分会委员

中国细胞生物学会发育生物学会分会委员

中国动物学会发育生物学专业委员会委员




代表性成果

1. Qu, C., Yang, W., Kan, Y., Zuo, H., Wu, M., Zhang, Q., Wang, H., Wang, D. and Chen, J.  RhoA/ROCK Signaling Regulates Drp1-Mediated Mitochondrial Fission During Collective Cell Migration. Frontiers in Cell and Developmental biology (2022)

2. Wang, X., Wang, H. , Liu, L., Li, S., Emery, G. and Chen, J.  Temporal coordination of collective migration and lumen formation by antagonism between two nuclear receptors. Iscience (2020a)

3. Wang, H. *, Guo, X., Wang, X., Wang, X. and Chen, J.  Supracellular actomyosin mediates cell-cell communication and shapes collective migratory morphology. Iscience (2020b)

4. Guo, X., Luo, J., Wang, H., and Chen, J. SERCA regulates collective cell migration by maintaining cytoplasmic Ca2+homeostasis, Journal of Genetics and Genomics (2019)

5. Wang, H., Qiu, Z., Xu, Z., Chen, S., Luo, J., Wang, X., and Chen, J .  aPKC is a key polarity molecule coordinating the function of three distinct cell polarities during collective migration, Development (2018)

6. Kang, D., Wang, D., Xu, J., Quan, C., Guo1, X., Wang, H., Luo, J., Yang, Z., Chen, S., and Chen, J .  The InR/Akt/TORC1 growth-promoting signaling negatively regulates JAK/STAT activity and migratory cell fate during morphogenesis, Developmental Cell (2018)

7. Wu, J., Wang, H., Xuan, G., Chen, J. Cofilin-mediated actin dynamics promotes actin bundle formation during Drosophila bristle development Molecular Biology of the Cell (2016)

8. Wan, P., Wang, D., Luo, J., Chu, D., Wang, H., Zhang, L., and Chen, J.  Guidance receptor promotes asymmetric distribution of Exocyst and recycling endosome during collective cell migration  Development  (2013).

9. Chu, D., Pan, H., Wan, P., Wu, J., Luo, J., Zhu, H. and Chen, J.  AIP1 Acts with Cofilin to Control Actin Dynamics during Epithelial Morphogenesis  Development 139:3561-3571. (2012)

10. Zhang, L., Luo, J., Wan, P., Wu, J., Laski, F. and Chen, J.  Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis. Development 138, 455-64. (2011)


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