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  • 李尔广

教授、博士生导师,医药生物技术国家重点实验室 

地址:南京市汉口路22号化学楼701210093

邮箱:erguang@nju.edu.cn









研究领域


微生物感染及应用



工作经历


2008-今,南京大学博士生导师

2008-今,南京大学医学院教授

2002-2008,美国思科瑞普斯研究所免疫系助教授(Assistant Professor

1998-2002,美国思科瑞普斯研究生高级研究助理(Associate Scientist

1993-1998,美国思科瑞普斯研究所(Scripps Research)博士后



荣誉奖励


2002-2004,美国NIN Research Career Development Award



学术任职


2019-,《Frontiers in Immunology(IF: 8.7) Associate Editor




代表性成果

(1)    Zhang D. Zhao YH, Wang LL, You XX, Li JJ, Zhang GH, Hou YY, Wang HW, He SS*, and Erguang Li*. Axl mediates resistance to respiratory syncytial virus infection independent of cell attachment. Am J Respiratory Cell Mol Biol, 2022;67(2):227-40.

(2)    Zhang D, Yang J, Zhao YH, Shan JJ, Wang LL, Yang G, He SS*, and E Li*. RSV infection in neonatal mice induces pulmonary eosinophilia responsible for asthmatic reaction. Frontiers in Immunology, 2022;13:817113.

(3)    Wang Q, Zhang Y, Zhang B, Fu Y, Zhao X, Zhang J, Zuo K, Xing Y, Jiang S, Qin Z, E Li, Guo H, Liu Z, Yang J*. Single-cell chromatin accessibility landscape in kidney identifies additional cell-of-origin in heterogenous papillary renal cell carcinoma. Nat Commun 2022, 13: 31. doi.org/10.1038/s41467-021-27660-3.

(4)    Wang LL, Xu DG, Huang Q, Yang G, Zhang MY, Bi JA, Shan JJ, Li E*, and SS He*. Characterization of tonsil microbiota and their effect on adenovirus reactivation in tonsillectomy samples. Microbiology Spectrum, 2021, 9, e01246-21.

(5)    Wang LL #, Guo HM #, Li JW, Cai XY, He SS, Yang G*, and E Li *. Adenovirus is prevalent in juvenile polyps and correlates with low vitamin D receptor expression. Pediatric Research, 2021, doi.org/10.1038/s41390-021-01697-y.

(6)    Wang LL, MY Zhang, JJ Li, G Yang, JW Li, HW Wang, SS He *, and E Li *, HDACi promotes latent adenovirus reactivation from tonsillectomy specimens. J Virol, 2020, 94:e00100-20.

(7)    Ren K, Zhang W, Chen X, Ma Y, Dai Y, Fan Y, Hou YY, RX Tan*, and E Li*. An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4. PLoS Pathogens 12(10): e1005950, 2016.

(8)    Ren K, Lv Y, Zhuo Y, Chen C. Shi H, Guo L, Yang G, Hou Y, Tan RX*, E Li*. Suppression of IRG-1 improves immune lung injury after RSV infection by reducing ROS production. J Virol, 90, 7313-7322, 2016.

(9)    Guo X, Liu T, Shi H, Hou Y, Tan RX and E Li*. NLRC5 induction regulates MHC II expression during RSV infection of airway epithelial cells. J Virol. 89. 7636-45, 2015.

(10) Chen XQ, Qiao HS, Liu X, Yang ZY, Xu LF, Xu YX, Ge HM, RX Tan* and E Li*. Inhibition of herpes simplex virus infection by oligomeric stilbenoids through ROS generation. Antiviral Res 95:30-36 (2012).


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