研究员、教师,医药生物技术国家重点实验室
地址:南京市栖霞区仙林大道163号,210023
邮箱:wenluo@nju.edu.cn
研究领域 |
心血管发育与疾病发生
工作经历 |
2008-2015,南京大学模式动物研究所 博士
2015-2020,西班牙国家心血管研究中心 博士后
2021-至今,南京大学现代生物研究院 助理教授 特聘研究员
荣誉奖励 |
2022,国家级海外青年人才计划
2022,江苏省特聘教授
代表性成果 |
[1] Luo W, Garcia-Gonzalez I, Fernandez-Chacon M, Casquero-Garcia V, Sanchez-Munoz MS, Muhleder S, et al. Arterialization requires the timely suppression of cell growth. Nature. 2021;589(7842):437-41.
[2] Xia M, Luo W, Jin H, Yang Z. HAND2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis. Development. 2019;146(13).
[3] Pontes-Quero S, Fernandez-Chacon M, Luo W, Lunella FF, Casquero-Garcia V, Garcia-Gonzalez I, et al. High mitogenic stimulation arrests angiogenesis. Nat Commun. 2019;10(1):2016.
[4] Fernandez-Chacon M, Casquero-Garcia V, Luo W, Francesca Lunella F, Ferreira Rocha S, Del Olmo-Cabrera S, et al. iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications. Nat Commun. 2019;10(1):2262.
[5] Pontes-Quero S, Heredia L, Casquero-Garcia V, Fernandez-Chacon M, Luo W, Hermoso A, et al. Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis. Cell. 2017;170(4):800-14 e18.
[6] Luo W, Zhao X, Jin H, Tao L, Zhu J, Wang H, et al. Akt1 signaling coordinates BMP signaling and beta-catenin activity to regulate second heart field progenitor development. Development. 2015;142(4):732-42.
[7] Zhao X, Lu S, Nie J, Hu X, Luo W, Wu X, et al. Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice. Mol Cell Biol. 2014;34(11):1966-75.
[8] Yuan B, Wan P, Chu D, Nie J, Cao Y, Luo W, et al. A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice. Am J Pathol. 2014;184(7):1967-80.
[9] Wang P, Mao B, Luo W, Wei B, Jiang W, Liu D, et al. The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy. Basic Res Cardiol. 2014;109(5):435.