研究员, PI, 南京大学博士生导师,医药生物技术国家重点实验室, 南京大学医学院模式动物研究所
地址:南京大学模式动物研究所南京市浦口区学府路12号,210032
邮箱:niikura@nicemice.cn
研究领域 |
癌症和脑干细胞分裂和细胞周期
工作经历 |
2018-,南京大学模式动物研究所研究员, Principal Investigator
2019-,南京大学博士生导师
荣誉奖励 |
2009,FASEB有丝分裂会议FASEB青年研究员奖, 在意大利托斯卡纳卢卡举行
学术任职 |
2022-,Guest associate editor of Frontiers in Cell and Developmental Biology
重要学术期刊审阅者
2022-Jun, JoVE, Peer Reviewer.
2022-Jun, Frontiers in Cell and Developmental Biology, Peer Reviewer.
2021-Apr, JoVE, Peer Reviewer.
Form 2019-Aug to 2019-Nov, BBA (Biochimica et Biophysica Acta), Peer Reviewer
代表性成果 |
1. *#Niikura Y, #Fang L, #Kitagawa R, Li P, Xi Y, You J, Gao Y, *Kitagawa K. Mass Spectrometry Analysis to Identify Ubiquitylation of EYFP-tagged CENP-A (EYFP-CENP-A). J. Vis. Exp. 2020(160). Epub 2020/07/01. doi: 10.3791/61138. PubMed PMID: 32597847. (# Equal contribution)
2. *#Niikura Y, #Kitagawa R, Fang L, *Kitagawa K. CENP-A Ubiquitylation Is Indispensable to Cell Viability. Dev Cell. 2019;50(6):683-9 e6. Epub 2019/09/25. doi: 10.1016/j.devcel.2019.07.015. PubMed PMID: 31550462; PMCID: PMC6761987. (#Equal contribution)
3. *#Niikura Y, Kitagawa R, *Kitagawa K. CENP-A Ubiquitylation Contributes to Maintaining the Chromosomal Location of the Centromere. Molecules. 2019;24(3). Epub 2019/01/27. doi: 10.3390/molecules24030402. PubMed PMID: 30678315.
4. #Niikura Y, Kitagawa R, Kitagawa K. The position of the centromere is marked with ubiquitylation of CENP-A. ATLAS of Science [Internet]. 2018 January 30, 2018. Available from: http://atlasofscience.org/the-position-of-the-centromere-is-marked-with-ubiquitylation-of-cenp-a/.
5. #Niikura Y, Kitagawa R, Ogi H, Kitagawa K. SGT1-HSP90 complex is required for CENP-A deposition at centromeres. Cell Cycle. 2017:1-12. doi: 10.1080/15384101.2017.1325039. PubMed PMID: 28816574.
6. #Niikura Y, Kitagawa R, Kitagawa K. CENP-A Ubiquitylation Is Required for CENP-A Deposition at the Centromere. Dev Cell. 2017;40(1):7-8. doi: 10.1016/j.devcel.2016.12.020. PubMed PMID: 28073011.
7. #Niikura Y Kitagawa R, Kitagawa K. The inheritance of centromere identity. Mol Cell Oncol. 2016;3(4):e1188226. doi: 10.1080/23723556.2016.1188226. PubMed PMID: 27652331; PMCID: PMC4972116 .
8. #Niikura Y, Kitagawa R, Kitagawa K. CENP-A Ubiquitylation Is Inherited through Dimerization between Cell Divisions. Cell Rep. 2016;15(1):61-76. Epub 2016/04/08. doi: 10.1016/j.celrep.2016.03.010. PubMed PMID: 27052173; PubMed Central PMCID: PMC4826857.
(Faculty of 1000, http://f1000.com/prime/726271180?bd=1)
9. #Niikura Y, Kitagawa K. Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins. J. Vis. Exp. 2016(109):e53732. doi: 10.3791/53732. PubMed PMID: 26967065.
10. #Niikura Y, Kitagawa R, Ogi H, Abdulle R, Pagala V, Kitagawa K. CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromere. Dev Cell. 2015;32(5):589-603. Epub 2015/03/03. doi: 10.1016/j.devcel.2015.01.024. PubMed PMID: 25727006; PubMed Central PMCID: PMC4374629.
图书
1. *#Niikura Y, Kitagawa K#. E3 Ligase for CENP-A (Part 2). In: Catala A, editor. London, UK: IntechOpen [one book chapter]; 2022.3.6.
2. *#Niikura Y, Kitagawa K#. E3 Ligase for CENP-A (Part 1). In: Catala A, editor. London, UK: IntechOpen [one book chapter]; 2022.1.24.
3. *#Niikura Y, *Kitagawa K. Function of SGT1, A co-chaperon. Heat Shock Protein 90 in Human Diseases and Disorders. Dordrecht, Netherlands: Springer Nature Publishers [Chapter 16]; 2019.12.13.
团队风采 |