副教授,医药生物技术国家重点实验室
地址:南京市栖霞区仙林大道163号,210023
邮箱:rhdu@nju.edu.cn
研究领域 |
心血管药理学,抗炎与代谢药理学
工作经历 |
2005-2013,南京大学医学院讲师
2013-,南京大学医学院副教授
荣誉奖励 |
2015-2016 国家留学基金委青年骨干教师
学术任职 |
国家自然科学基金和江苏省自然科学基金函评专家
Scientific reports、International pharmacology 等杂志审稿人
代表性成果 |
[1] Xue W, Yu Y, Yao Y, Zhou L, Huang Y, Wang Y, Chen Z, Wang L, Li X, Wang X, Du R, Shen Y, Xu Q. Breast cancer cells have an increased ferroptosis risk induced by system xc blockade after deliberately downregulating CYTL1 to mediate malignancy. Redox Biology. 2024; 70:103034.
全文链接:https://pubmed.ncbi.nlm.nih.gov/32621955/38211443
[2] Xu Z, Li X, Ding Z, Zhang Y, Peng Z, Yang X, Cao W, Du R. LRPPRC inhibits autophagy and promotes foam cell formation in atherosclerosis. FEBS J. 2022 Dec;289(23):7545-7560.
全文链接:https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16567
[3] Xu Z, Zhang M, Li X, Wang Y, Du R. Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels. Int J Mol Sci. 2022;23(7):3788-3804.
全文链接:https://www.mdpi.com/1422-0067/23/7/3788
[4] Ding W, Ding Z, Wang Y, Zhu Y, Gao Q, Cao W, Du R. Evodiamine attenuates experimental colitis injury via activating autophagy and inhibiting NLRP3 inflammasome assembly. Frontiers in Pharmacology.2020;11:573870.
全文链接:https://www.frontiersin.org/articles/10.3389/fphar.2020.573870/full
[5] Gao Q , Wei A, Chen F, Chen X, Ding W, Ding Z, Wu Z, Du R, Cao W. Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice. Pharmacol Res. 2020;160:105059.
全文链接:https://pubmed.ncbi.nlm.nih.gov/32621955/
[6] Zhang Q1, Du R1, Reis Monteiro Dos Santos GR, Yefidoff-Freedman R, Bohm A, Halperin J, Chorev M, Aktas BH.New activators of eIF2α Kinase Heme-Regulated Inhibitor (HRI) with improved biophysical properties. Eur J Med Chem. 2020;187:111973.
全文链接:https://pubmed.ncbi.nlm.nih.gov/31881453/
[7]Cao Y, Ding W, Zhang J, Gao Q, Yang H, Cao W, Wang Z, Fang L, Du R. Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion. J Proteome Res. 2019;18(5):2032-2044.
全文链接:https://pubs.acs.org/doi/10.1021/acs.jproteome.8b00921
[8]Qin T1, Du R1, Huang F, Yin S, Yang J, Qin S, Cao W. Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy. Free Radical Bio Med. 2016;92:90-99.
全文链接:https://linkinghub.elsevier.com/retrieve/pii/S0891-5849(16)00012-5
[9]Du RH, Qin SY, Shi LS, Zhou ZQ, Zhu XY, Liu J, Tan RX, Cao W. Fumigaclavine C activates PPARγ pathway and attenuates atherogenesis in ApoE-deficient mice. Atherosclerosis. 2014;234(1):120-128
全文链接:https://linkinghub.elsevier.com/retrieve/pii/S0021-9150(14)00114-2
团队风采 |