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  • 陈兵

主任医师,博士生导师,南京大学医学院附属鼓楼医院血液科行政主任,医药生物技术国家重点实验室 

地址:南京市栖霞区仙林大道163号,210023

邮箱:chenbing1@nju.edu.cn









研究领域


多发性骨髓瘤的基础与临床研究 

恶性血液病生物免疫治疗研究




工作经历


2014-,南京大学医学院附属鼓楼医院血液科主任医师

2017-,南京大学医学院附属鼓楼医院血液科行政主任

2019-,南京大学博士生导师



荣誉奖励


2012,江苏省科学技术进步奖三等奖

2013,江苏省医学新技术引进奖一等奖

2017,江苏省医学新技术引进奖二等奖

2017,江苏省“科教强卫工程”创新团队领军人才

2020,江苏省医学新技术引进奖一等奖



学术任职


2019-,江苏省医学会血液学分会委员兼学术秘书

2019-,江苏省免疫学会血液免疫学专业委员会副主任委员

2020-,中华医学会血液学分会浆细胞病学组委员

2020-,中国医药教育协会血液专业委员会常务委员

2021-,江苏省抗癌协会血液肿瘤专委会副主任委员

2021-,江苏省医学会血液学分会浆细胞疾病学组组长




代表性成果

[1]    Ming Sun#, Peipei Xu#, Enxiu Wang, Min Zhou, Tongpeng Xu, Jing Wang, Qian Wang, Bo Wang, Kaihua Lu*, Chen Wang*, Bing Chen*. Novel two-chain structure utilizing KIRS2/DAP12 domain improves the safety and efficacy of CAR-T cells in adults with r/r B-ALL.  Molecular Therapy: Oncolytics. Volume 23, 17 December 2021, Pages 96-106. 

原文链接:https://doi.org/10.1016/j.omto.2021.08.014.

[2]    Tian Xia, Ming Liu, Quan Zhao, Jian Ouyang*, Peipei Xu*and Bing Chen*. PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma. Cell Death and Disease (2021) 12:851.

原文链接:https://doi.org/10.1038/s41419-021-04125-5.

[3]    Hua Bai*, Min Zhou, He Zhou, Qiaoyan Han, Han Xu, Peipei Xu*, Bing Chen*. Licochalcone A suppresses Sp1 expression with potential anti-myeloma activity. Cancer Communications.2021;41:1239–1242

原文链接:https://doi.org/10.1002/cac2.12223.

[4]    Dong Xiaoqing; Zuo Yifan; Zhou Min; Sun Jingjing; Xu Peipei*; Chen Bing*. Bortezomib activation of mTORC1 pathway mediated by NOX2-drived reactive

oxygen species results in apoptosis in primary dorsal root ganglion neurons, Experimental Cell Research, 2021, 400(2).

原文链接:https://doi.org/10.1016/j.yexcr.2021.112494.

[5]  Guangtao Gao#, Mengkun Fang#, Peipei Xu*, Bing Chen*. Identification of three immune molecular subtypes associated with immune profiles, immune checkpoints, and clinical outcome in multiple myeloma. Cancer Medicine. 2021;10:7395–7403.

原文链接:https://doi.org/10.1002/cam4.4221.

[6] Jing Wang#, Min Zhou#, Rongfu Zhou, Jingyan Xu* and Bing Chen*. Nomogram for Predicting the Overall Survival of Adult Patients With Primary Gastrointestinal Diffuse Large B Cell Lymphoma: A SEER Based Study. Frontiers in Oncology. July 2020, 10:1093.

原文链接:https://doi.org/10.3389/fonc.2020.01093.

[8] Bing Chen#, Min Zhou#, Hai Zhang, Chen Wang, Xiaocui Hu, Bo Wang* & Enxiu Wang. TREM1/Dap12-based CAR-T cells show potent antitumor activity. Immunotherapy. 2019 Aug;11(12):1043-1055.

原文链接:https://doi.org/10.2217/imt-2019-0017.

[9] Zhou Di# ; Xu Peipei#; Zhou Xuan; Diao Zhenyu; Ouyang Jian*; Yan Guijun*; Chen Bing*. MiR-181a enhances drug sensitivity of mixed lineage leukemia-rearranged acute myeloid leukemia by increasing poly(ADP-ribose) polymerase1 acetylation. Leukemia & Lymphoma. 2020, 62(1): 136-146. 

原文链接:https://doi.org/10.1080/10428194.2020.1824067.

10.Dan Guo#, Peipei Xu#, Dangui Chen#, Lili Wang, Yudi Zhu, Yifan Zuo, Bing Chen*. Daunorubicin-Loaded CdTe QDs Conjugated with Anti-CD123 mAbs: A Novel Delivery System for Myelodysplastic Syndromes Treatment. Int J Nanomedicine. 2020 Jan 24;15:521-536. 

原文链接:https://doi.org/10.2147/IJN.S233395.


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