主任医师、东部战区总医院神经外科主任、全军神经外科研究所所长
地址:南京市玄武区中山东路305号,210002
邮箱:machiyuan_nju@126.com
研究领域 |
脑肿瘤的精准治疗
工作经历 |
2003-,东部战区总医院
2020-,南京大学教授
2021-,东部战区总医院神经外科主任
荣誉奖励 |
1. 2010年,颅内动脉瘤的基础与临床研究 教育部科学进步一等奖(排名6/10)
2. 2015年,王忠诚中国神经外科医师奖青年奖
学术任职 |
中华医学会神经外科学分会青年委员会副主任委员
江苏省医学会神经外科学分会常务委员
国家卫健委脑出血外科诊疗能力提升项目专家委员会青委执行主委
中国研究型医院协会神经微侵袭专委会副主委
代表性成果 |
1. BTB domain and CNC homolog 1 promotes glioma invasion mainly through regulating extracellular matrix and increases ferroptosis sensitivity. Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1;1868(12):166554.
2. Roles of the m6A Modification of RNA in the Glioblastoma Microenvironment as Revealed by Single-Cell Analyses.[J] .Front Immunol, 2022, 13: 798583.
3. Current WHO Guidelines and the Critical Role of Genetic Parameters in the Classification of Glioma: Opportunities for Immunotherapy.[J] .Curr Treat Options Oncol, 2022, 23: 188-198.
4. A Novel Immune Classification for Predicting Immunotherapy Responsiveness in Patients With Adamantinomatous Craniopharyngioma.[J] .Front Neurol, 2021, 12: 704130.
5. BACH1 as a potential target for immunotherapy in glioblastomas.[J] .Int Immunopharmacol, 2022, 103: 108451.
6. ACT001 reverses resistance of prolactinomas via AMPK-mediated EGR1 and mTOR pathways.[J] .Endocr Relat Cancer, 2021, 29: 33-46.
7. Development and Validation of Nomogram to Preoperatively Predict Intraoperative Cerebrospinal Fluid Leakage in Endoscopic Pituitary Surgery: A Retrospective Cohort Study.[J] .Front Oncol, 2021, 11: 719494.
8. Curcumin Sensitizes Prolactinoma Cells to Bromocriptine by Activating the ERK/EGR1 and Inhibiting the AKT/GSK-3β Signaling Pathway In Vitro and In Vivo.[J] .Mol Neurobiol, 2021, 58: 6170-6185.
9. A Nomogram for Preoperatively Predicting the Ki-67 Index of a Pituitary Tumor: A Retrospective Cohort Study.[J] .Front Oncol, 2021, 11: 687333.
10. Glioma-Associated Stromal Cells Stimulate Glioma Malignancy by Regulating the Tumor Immune Microenvironment.[J] .Front Oncol, 2021, 11: 672928.
团队风采 |