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  • 张冬梅

教授,医药生物技术国家重点实验室 

地址:南京市栖霞区仙林大道163号,210023

邮箱:zdm@nju.edu.cn









研究领域


代谢综合征肾损伤病理机制及中药的保护作用



工作经历


2018-,南京大学教授

2008-,硕士生导师



荣誉奖励


2020, 宝钢优秀教师奖(1/1

2019, 高等学校科学研究优秀成果奖(科学技术)一等奖 (4/5)

2014, 江苏省六大人才高峰高层次人才培养计划 A (1/4)



学术任职


2015- 中国生物化学与分子生物学学会会员

2017- 中国生物物理学会(自由基生物学与自由基医学分会)会员




代表性成果

[1] J. Zhou, J. Yang, Y.M. Wang, H. Ding, T.S. Li, Z.H. Liu, L. Chen, R.Q. Jiao, D.M. Zhang*, L.D. Kong*. IL-6/STAT3 signaling activation exacerbates high fructose-induced podocyte hypertrophy by ketohexokinase-A-mediated tristetraprolin down-regulation. Cell. Signal. 202186, 110082. 

全文链接:https://www.webofscience.com/wos/alldb/full-record/WOS:000689714700003

[2] T.T. Gu#, D.M. Zhang#, Z.Y. Wan, T.S. Li, R.Q. Jiao, T.Y. Chen, X.J. Zhao, L.D. Kong*. Polydatin enhances glomerular podocyte autophagy homeostasis by improving Nrf2-dependent antioxidant capacity in fructose-fed rats. Mol. Cell. Endocrinol2021520, 111079.  

全文链接:https://www.webofscience.com/wos/alldb/full-record/WOS:000600756700012

[3] L.L. Kang, D.M. Zhang, R.Q. Jiao, S.M. Pan, X.J. Zhao, Y.J. Zheng, T.Y. Chen, L.D. Kong*. Pterostilbene Attenuates Fructose-Induced Myocardial Fibrosis by Inhibiting ROS-Driven Pitx2c/miR-15b Pathway. Oxid. Med. Cell. Longev2019, 1243215. 

全文链接:https://www.webofscience.com/wos/alldb/full-record/WOS:000503779300004

[4] L. Gao, X.C. Lu*, H. Liu, J. Li, W.J. Li, R.B. Song, R.Y. Wang, D.M. Zhang, J.J. Zhu. Mediation of Extracellular Polymeric Substances in Microbial Reduction of Hematite by Shewanella oneidensis MR-1. Front. Microbiol20199, 1490.

全文链接:https://www.webofscience.com/wos/alldb/full-record/WOS:000462716200001

[5] T.T. Gu#, T.Y. Chen, Y.Z. Yang, X.J. Zhao, Y. Sun, T.S. Li, D.M. Zhang*, L.D. Kong*. Pterostilbene alleviates fructose-induced renal fibrosis by suppressing TGF-beta1/TGF-beta type I receptor/Smads signaling in proximal tubular epithelial cells. Eur. J. Pharmacol2019842: 70-78. 

全文链接:https://www.webofscience.com/wos/alldb/full-record/WOS:000453397300009

[6] M.Z. Zuo, W.R. Qian, Z.Q. Xu, W. Shao, X.Y. Hu*, D.M. Zhang*, J.L. Qiang*, X.Q. Sun, L.Y. Wang. Multi-Responsive Supramolecular Theranostic Nanoplatform Based on Pillar[5]arene and Diphenylboronic Acid Derivatives for Integrated Glucose Sensing and Insulin Delivery. Small2018, 1801942.

全文链接:https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201801942

[7] Y.J. Zheng, Y.M. Li, H.Y. Long, X.J. Zhao, K.K. Jia, J. Li, L.Y. Wang, R.Y. Wang, X.C. Lu, D.M. Zhang*. bifARegulates Biofilm Development of Pseudomonas putida MnB1 as a Primary Response to H2O2 and Mn2+Front. Microbiol20189, 1490. 

全文链接:https://www.webofscience.com/wos/alldb/full-record/WOS:000438065300001

[8]  张冬梅、陈钧辉主编,《普通生物化学》(第6版),高等教育出版社,北京,2021115.0万字)

[9] 李俊、张冬梅、陈钧辉主编,《生物化学实验》(第6版),科学出版社,北京,202053.1万字)


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