2018-，南京大学 副教授，博导

2024-，南京大学附属鼓楼医院，研究员（兼）  

2014-2018，香港浸会大学 研究助理教授

2012-2014，香港浸会大学，博士后

2012-2013，美国布朗大学，访问学者

2009-2012，香港中文大学，博士（PH.D.）

2008-2009，香港理工大学，研究助理

2013，香港中文大学优秀青年学者学位论文奖

2011，美国骨矿研究学会（ASBMR）青年研究学者奖

2010，中华医学会骨质疏松及骨矿盐疾病分会暨国际华人骨研学会（ICMRS），WEB JEE TRAVEL AWARD

2024-2028，中国老年学和老年医学学会老年骨科分会基础学组委员

2021-2025，中国医师协会骨科医师分会第五届委员会骨科基础学组委员

2019-2023，中国老年学和老年医学学会老年骨科分会创新转化学组第一届委员

2015-2019，中华中医药学会免疫学分会委员

[1]. Xian Y#, Liu B#, Shen T, Yang L, Peng R, Shen H, An X, Wang Y, Ben Y, Jiang Q*, Guo B*. Enhanced SIRT3 expression restores mitochondrial quality control mechanism to reverse osteogenic impairment in type 2 diabetes mellitus. Bone Res. 2025;13(1):30.

[2]. Shi T#, Shen S#, Shi Y#, Wang Q, Zhang G, Lin J, Chen J, Bai F, Zhang L, Wang Y, Gong W, Shao X, Chen G, Yan W, Chen X, Ma Y, Zheng L, Qin J, Lu K, Liu N, Xu Y, Shi YS*, Jiang Q*, Guo B*. Osteocyte-derived sclerostin impairs cognitive function during ageing and Alzheimer's disease progression. Nat Metab. 2024;6(3):531-549. 

[3]. Liu B#, Xian Y#, Chen X, Shi Y, Dong J, Yang L, An X, Shen T, Wu W, Ma Y, He Y, Gong W, Peng R, Lin J, Liu N, Guo B*, Jiang Q*. Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis. Adv Sci (Weinh). 2024:e2307338.

[4]. Shao X, Gong W, Wang Q, Wang P, Shi T, Mahmut A, Qin J, Yao Y, Yan W, Chen D, Chen X*, Jiang Q*, Guo B*. Atrophic skeletal muscle fibre-derived small extracellular vesicle miR-690 inhibits satellite cell differentiation during ageing. J Cachexia Sarcopenia Muscle. 2022;13(6):3163-3180.

[5]. Chen X#, Zhang L#, Shao X, Gong W, Shi T, Dong J, Shi Y, Shen S, He Y, Qin J, Lu J, Jiang Q*, Guo B*. Specific Clearance of Senescent Synoviocytes Suppresses the Development of Osteoarthritis based on Aptamer-Functionalized Targeted Drug Delivery System., Adv. Funct. Mater. 2022, 32, 2109460.

[6]. Zhang L#, Chen X#, Cai P*, Sun H, Shen S, Guo B*, Jiang Q*. Reprogramming Mitochondrial Metabolism in Synovial Macrophages of Early Osteoarthritis by a Camouflaged Meta-Defensome. Adv Mater. 2022;34(30):e2202715.

[7]. Chen X#, Gong W#, Shao X, Shi T, Zhang L, Dong J, Shi Y, Shen S, Qin J, Jiang Q*, Guo B*. METTL3-mediated m6A modification of ATG7 regulates autophagy-GATA4 axis to promote cellular senescence and osteoarthritis progression. Ann Rheum Dis. 2022;81(1):87-99.

[8]. Liang C#, Guo B#, Wu H#, Shao N, Li D, Liu J, Dang L, Wang C, Li H, Li S, Lau WK, Cao Y, Yang Z, Lu C, He X, Au DW, Pan X, Zhang BT, Lu C, Zhang H, Yue K, Qian A, Shang P, Xu J, Xiao L, Bian Z, Tan W, Liang Z, He F, Zhang L*, Lu A*, Zhang G*. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy. Nat Med. 2015;21(3):288-94.

[9]. Wang X#, Guo B#, Li Q, Peng J, Yang Z, Wang A, Li D, Hou Z, Lv K, Kan G, Cao H, Wu H, Song J, Pan X, Sun Q, Ling S, Li Y, Zhu M, Zhang P, Peng S, Xie X, Tang T, Hong A, Bian Z, Bai Y, Lu A, Li Y, He F, Zhang G*, Li Y*. miR-214 targets ATF4 to inhibit bone formation. Nat Med. 2013;19(1):93-100.

[10]. Zhang G*, Guo B#, Wu H#, Tang T#, Zhang BT#, Zheng L, He Y, Yang Z, Pan X, Chow H, To K, Li Y, Li D, Wang X, Wang Y, Lee K, Hou Z, Dong N, Li G, Leung K, Hung L, He F, Zhang L*, Qin L*. A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nat Med. 2012;18(2):307-14.