南京市栖霞区仙林大道163号，210023
jiayuchen@nju.edu.cn
工作经历
2021-，南京大学，生命科学学院，特聘研究员
2021-，南京大学，化学与生物医药创新研究院，特聘研究员
2016-2021, 加州大学圣地亚哥分校，博士后
荣誉奖励
2025，江苏省杰出青年
2025，南京大学“师德先进”青年教师奖
2024，教育部青年长江学者
2021，江苏特聘教授
2019，K99/R00: Pathway to Independence Award
2014，吴瑞奖
学术任职
2025-至今，中国卒中学会多组学分会专委
代表性成果
[1] H. Xu#, J. Ye#, K. X. Zhang#, Q. Hu, T. Cui, C. Tong, M. Wang, H. Geng, K. M. Shui, Y. Sun, J. Wang, X. Hou, K. Zhang, R. Xie, Y. Yin, N. Chen, & J. Y. Chen*. Chemoproteomic profiling unveils binding and functional diversity of endogenous proteins that interact with endogenous triplex DNA. Nat Chem. 2024, 16(11), 1811-1821.
[2] J. Hu#, Z. Xing#, H. Yang#, Y. Zhou#, L. Guo, X. Zhang, L. Xu, Q. Liu, J. Ye, X. Zhong, J. Wang, R. Lin, E. Long, J. Jiang, L. Chen, Y. Pan, L. He* & J. Y. Chen*. Deep learning-enhanced R-loop prediction provides mechanistic implications for repeat expansion diseases. iScience, 2024, 27(8), 110584.
[3] J. Hu #, Z. Zhang #, S. Xiao, Y. Cao, Y. Chen, J. Weng, H. Jiang*, W. Li*, J. Y. Chen*, & C. Liu*. Microhomology-mediated circular DNA formation from oligonucleosomal fragments during spermatogenesis. Elife, 2023, 12.
[4] R. Lin#, X. Zhong#,*, Y. Zhou#, H. Geng, Q. Hu, Z. Huang, J. Hu, X. D. Fu, L. Chen* and J. Y. Chen*. R-loopBase: a knowledgebase for genome-wide R-loop formation and regulation. Nucleic Acids Res. 2022, 50(D1): D303-D315
[5] R. Xiao#, J. Y. Chen#, Z. Liang#, D. Luo, G. Chen, Z. J. Lu, Y. Chen, B. Zhou, H. Li, X. Du, Y. Yang, M. San, X. Wei, W. Liu, E. Lecuyer, B. R. Graveley, G. W. Yeo, C. B. Burge, M. Q. Zhang, Y. Zhou and X. D. Fu*. Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. Cell. 2019,178(1):107-121.e18.