南京市栖霞区仙林大道163号，210023
zhenhuang@nju.edu.cn
工作经历
2022.09-至今，南京大学，生命科学学院，教授
2015.09-2022.08，南京大学，生命科学学院，副教授
2013.07-2015.08，南京大学，生命科学学院，博士后
荣誉奖励
2020年，作为《生物化学》教学团队成员，获“南京大学优秀教学团队”称号
2019年，获南京大学新华报业优秀青年教师奖
学术任职
代表性成果
1. Shiliang Ji, Feifan Wang, Yongjie Wu , Haoran Hu, Zhen Xing, Jie Zhu, Shi Xu, Tiyun Han, Guilai Liu, Zengding Wu, Caiyi Fei, Lingming Kong, Jiangning Chen, Zhi Ding*, Zhen Huang*, Junfeng Zhang*. Large-scale transcript variants dictate neoepitopes for cancer immunotherapy. Sci Adv. 2025;11(5):eado5600.
2. Junqing Hu, Feilong Guo, Congwei Han, Qiqi Zhao, Huaiqiang Yi, Jinhao Xu, Huijie Jia, Yongjie Wu, Lei Dong, Xiaoming Kao, Guoli Li*, Jiangning Chen*, Junfeng Zhang*, Zhen Huang*. CD169+ macrophages identify and eliminate tumor cells in colorectal cancer through CD169/CD43 interaction and FasL-driven apoptosis. Cell Rep. 2025;44(10):116351.
3. Chuancheng Gao, Fangling Hong, Yao Dong, Yong Fu, Yunong Ma, Xuedi Sun, Junfeng Zhang*, Jiangning Chen*, Zhen Huang*. Lifespan-regulated CAR-macrophages from myeloid progenitors for enhanced colorectal cancer therapy. Adv Sci. 2025;12(43):e17677.
4. Xiaohui Cheng, Pingwen Shao, XinTong Wang, Juan Jiang, Jiahui Chen, Jie Zhu, Weiming Zhu, Yi Li*, Junfeng Zhang*, Jiangning Chen*, Zhen Huang*. Myeloid-derived suppressor cell accumulation drives intestinal fibrosis through mCCL6/hCCL15 chemokine-mediated fibroblast activation. Adv Sci. 2025;12(8):e2411711.
5. Mingyue Li, Xintong Wang, Wenjie Hu, Xiaohui Cheng, Qi Sun, Yongjie Wu, Zhen Huang*, Jiangning Chen*. Intestinal epithelial C/EBPβ deficiency impairs colitis-associated tumorigenesis by disrupting CXCL1/CXCL2/CXCL5-CXCR2-mediated neutrophil infiltration. Acta Biochim Biophys Sin. 2025. doi: 10.3724/abbs.2025119.