工作经历
2019.12~至今 南京大学医学院 副教授
2015.09~2019.11 南京大学医学院 副研究员
荣誉奖励
[1] 2018年,《抗肿瘤纳米药物制备的关键技术及其应用》,教育部技术发明一等奖(第3完成人);
[2] 2018年,南京市高层次人才(高校C类人才);
[3] 2019年,《一种制备用于体内递送药理活性物质的蛋白纳米粒的方法》,江苏省专利金奖(主要专利发明人);
[4] 2021年,《基于生物材料为载体的纳米药物基础研究》,教育部自然科学一等奖(第4完成人);
[5] 2022年,江苏省第六期333高层次人才(第三层次)
学术任职
中国药学会 会员;中国化学会 会员;
Nature Communications, Advanced Materials、ACS Nano、J Controlled Release等期刊审稿人
代表性成果
[1] Yuxiang Wang, Jing Chen, Rumeng Duan, Rong Gu, Weiran Wang, Jinhui Wu, Huibo Lian*, Yiqiao Hu*, Ahu Yuan*,High-Z-Sensitized Radiotherapy Synergizes with the Intervention of the Pentose Phosphate Pathway for In Situ Tumor Vaccination,Advanced Materials, 2022
[2] Zhusheng Huang, Dan Yao, Jinhui Wu, Yiqiao Hu* and Ahu Yuan*, Gadolinium–Zoledronic acid Coordination Polymer Nanorods for Improved Tumor Radioimmunotherapy by Synergetically Inducing Immungenic Cell Death and Reprogramming Immunosuppressive Microenvironment, ACS nano, 2021, 15, 5, 8450–8465
[3] Zhusheng Huang, Yuxiang Wang, Dan Yao, Jinhui Wu, Yiqiao Hu*, Ahu Yuan*, Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress, Nat Commun, 2021 Jan 8;12(1)
[4] Yuxiang Wang, Yawen Ding, Dan Yao, Hong Dong, Changwei Ji*, Jinhui Wu, Yiqiao Hu* and Ahu Yuan*, Copper-Based Nanoscale Coordination Polymers Augmented Tumor Radioimmunotherapy for Immunogenic Cell Death Induction and T-Cell Infiltration, Small 2021, 17, 2006231
[5] Li Wang, Zhicheng Zhang, Yawen Ding, Jinhui Wu, Yiqiao Hu* and Ahu Yuan*,Novel copper-based and pH-sensitive nanomedicine for enhanced chemodynamic therapy, Chem. Commun., 2020, 56
[6] Shaoju Gan, Xiaoning Tong , Yue Zhang, Jinhui Wu, Yiqiao Hu*, and Ahu Yuan*,Covalent Organic Framework-Supported Molecularly Dispersed Near-Infrared Dyes Boost Immunogenic Phototherapy against Tumors,Advanced Functional Materials, 2019, 29, 1902757 (Cover Story)
[7] W. Wang, Y. Cheng, P. Yu, H. Wang, Y. Zhang, H. Xu, Q. Ye, A. Yuan*, Y. Hu*, J. Wu*, Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy, Nat Commun 10(1) (2019) 1580.
[8] Meng, L; Cheng, Y; Tong, X; Gan, S; Ding, Y; Zhang, Y; Wang, C; Xu, L; Zhu, Y; Wu, J*; Hu, Y*; Yuan, A*. Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition Via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects. ACS Nano 2018 Aug 28;12(8):8308-8322.