工作经历
2025-今,东部战区总医院急诊医学科,主任/主任医师
2023-2025,东部战区总医院战创伤救治中心,主任/副主任医师
2015-2022,东部战区总医院普通外科/重症医学科,副主任医师
2011-2015,东部战区总医院普通外科,主治医师
2010-2011,东部战区总医院普通外科,医师
荣誉奖励
2019,损伤控制性外科技术在急性肠缺血疾病的临床应用. 江苏省卫生健康委员会医学新技术引进奖二等奖(第一完成人)
2015,腹部创伤治疗理念创新与技术进步. 江苏医学科技奖一等奖(第一完成人)
学术任职
2023-今,《World Journal of Clinical Cases》(IF 1.0)Editor
2023-今,《World Journal of Gastroenterology》(IF 5.7)Editor
2023-今,《World Journal of Gastrointestinal Surgery》(IF 1.8)Editor
2023-今,《World Journal of Hepatology》(IF 2.5)Editor
代表性成果
[1]Chen F, Chu C, Wang X, et al. Tranexamic acid is associated with improved intestinal barrier function in traumatic hemorrhagic shock: A clinical prospective cohort study. Crit Care. 2025;29(1):353.
[2]Chu C, Wang X, Yang C, Chen F, Shi L, Xu W, Wang K, Liu B, Wang C, Sun D, Ding W*. Neutrophil extracellular traps drive intestinal microvascular endothelial ferroptosis by impairing Fundc1-dependent mitophagy. Redox Biol. 2023 Nov;67:102906.
[3]Wang X, Qiu H, Chu C, Wang K, Lu B, Yang C, Liu B, Lan G, Ding W*. Dual-Responsive Microsphere based on Natural Sunflower Pollen for Hemostasis and Repair in Inflammatory Bowel Disease. ACS Appl Mater Interfaces. 2024 Jun 19;16(24):30658-30670.
[4]Duan Z, Xie T, Chu C, Chen F, Wang X, Li J, Ding W*. De-escalation antibiotic therapy alleviates organ injury through modulation of NETs formation during sepsis. Cell Death Discov. 2021 Nov 10;7(1):345.
[5]Chen F, Chu C, Wang X, Yang C, Deng Y, Duan Z, Wang K, Liu B, Ji W, Ding W*. Hesperetin attenuates sepsis-induced intestinal barrier injury by regulating neutrophil extracellular trap formation via the ROS/autophagy signaling pathway. Food Funct. 2023 May 11;14(9):4213-4227.
[6]Sun S, Duan Z, Wang X, Chu C, Yang C, Chen F, Wang D, Wang C, Li Q, Ding W*. Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway. Cell Death Dis. 2021 Jun 11;12(6):606.
[7]Chu C, Wang X, Chen F, Yang C, Shi L, Xu W, Wang K, Liu B, Wang C, Sun D, Li J, Ding W*. Neutrophil extracellular traps aggravate intestinal epithelial necroptosis in ischaemia-reperfusion by regulating TLR4/RIPK3/FUNDC1-required mitophagy. Cell Prolif. 2024 Jan;57(1):e13538.
[8]Wang X, Chu C, Wang L, Chen F, Yang C, Deng Y, Wang K, Liu B, Li J, Ding W*. Sequential changes in body composition and metabolic response after pancreatic trauma. Nutrition. 2023 Jul;111:112036.
[9]Wang H, Shi L, Zhang Z, et al. Fructose-Modified Chitosan/Gelatin 3D Composite Sponge for enhanced Rapid Hemostasis. Biomacromolecules. 2025;26(2):1283-1293.
[10]Liu B, Deng Y, Duan Z, Chu C, Wang X, Yang C, Li J, Ding W*. Neutrophil extracellular traps promote intestinal barrier dysfunction by regulating macrophage polarization during trauma/hemorrhagic shock via the TGF-β signaling pathway. Cell Signal. 2024 Jan;113:110941.
[11]创伤急救彩色图谱,浙江大学出版社,2023年
[12]重症创伤生命支持,浙江大学出版社,2021年