2012-2017，清华大学，博士

2017-2022，美国加州大学旧金山分校，博士后

2022-2025，美国加州大学旧金山分校，Associate Specialist 

2025-至今，南京大学现代生物研究院，准聘助理教授，研究员

2025-至今，南京大学至诚青年教授

2025 优秀青年科学基金（海外）

[1] Ren X, Zheng L, Liu Y, Maliskova L, Tam TW, Sun Y, Liu H, Cui X, Lee J, Takagi MA, Li B, Ren B, Wang W, Shen Y#. CRISPR tiling deletion screens reveal functional enhancers and allelic compensation effects (ACE) on SIN3A transcription.

[2] Cui X*, Yang H*, Cai C, Beaman C, Yang X, Liu H, Ren X, Amador Z, Jones IR, Keough KC, Zhang M, Fair T, Abnousi A, Mishra S, Ye Z, Hu M, Pollen AA, Pollard KS, Shen Y#. Comparative characterization of human accelerated regions in neurons. Nature. 2025 Apr;640(8060):991-999.

[3] Ren X*, Yang H*, Nierenberg JL, Sun Y, Chen J, Beaman C, Pham T, Nobuhara M, Takagi MA, Narayan V, Li Y, Ziv E, Shen Y#. High-throughput PRIME-editing screens identify functional DNA variants in the human genome. Mol Cell. 2023 Dec 21;83(24):4633-4645.e9.

[4] Yang X, Wen J, Yang H, Jones IR, Zhu X, Liu W, Li B, Clelland CD, Luo W, Wong MY, Ren X, Cui X, Song M, Liu H, Chen C, Eng N, Ravichandran M, Sun Y, Lee D, Van Buren E, Jiang MZ, Chan CSY, Ye CJ, Perera RM, Gan L, Li Y#, Shen Y#. Functional characterization of Alzheimer's disease genetic variants in microglia. 

Nat Genet. 2023 Oct;55(10):1735-1744.

[5] Ren X, Wang M, Li B, Jamieson K, Zheng L, Jones IR, Li B, Takagi MA, Lee J, Maliskova L, Tam TW, Yu M, Hu R, Lee L, Abnousi A, Li G, Li Y, Hu M, Ren B, Wang W, Shen Y#. Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath. Sci Adv. 2021 Sep 17;7(38):eabi4360.

[6] Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M, Tam TW, Jamieson K, Lu SY, Ming GL, Li Y, Yao J, Weiss LA, Dixon JR, Judge LM, Conklin BR, Song H, Gan L, Shen Y#. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes. Nat Genet. 2019 Aug;51(8):1252-1262.

[7] Jia Y*, Xu RG*, Ren X*, Ewen-Campen B*, Rajakumar R, Zirin J, Yang-Zhou D, Zhu R, Wang F, Mao D, Peng P, Qiao HH, Wang X, Liu LP, Xu B, Ji JY, Liu Q, Sun J#, Perrimon N#, Ni JQ#. Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4719-4724.

[8] Ren X*, Yang Z*, Xu J*, Sun J*, Mao D*, Hu Y, Yang SJ, Qiao HH, Wang X, Hu Q, Deng P, Liu LP, Ji JY, Li JB#, Ni JQ#. Enhanced specificity and efficiency of the CRISPR/Cas9 system with optimized sgRNA parameters in Drosophila. Cell Rep. 2014 Nov 6;9(3):1151-62.

[9] Ren X*, Sun J*, Housden BE, Hu Y, Roesel C, Lin S, Liu LP, Yang Z, Mao D, Sun L, Wu Q, Ji JY, Xi J, Mohr SE, Xu J#, Perrimon N#, Ni JQ#. Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19012-7.