工作经历
2025-,南京大学现代生物研究院,研究员/助理教授
2017-2025,美国德州大学西南医学中心,博士后
2016-2017,美国科罗拉多大学博尔德分校,访问学生
2010-2016,复旦大学,博士
2006-2010,四川大学,本科
荣誉奖励
2025年入选国家级青年人才项目(海外优青)
学术任职
代表性成果
[1]. Zhu, X., Cruz, VE., Zhang, H., Erzberger, JP., and Mendell, JT. (2024). Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes. Science, 386 (6724), eadq8587
[2]. Hu, L. Zhang, Y., Guo, L., Zhong, H., Xie, L., Zhou, J., Liao, C., Yao, H., Fang, J., Liu, H., Zhang, C., Zhang, H., Zhu, X., Luo, M., Kriegsheim, AV., Li, B., Luo, ., Zhang, X., Chen, X., Mendell, JT., Xu, L., Kapur, P., Baldwin, AS., Brugarolas, J., Zhang, Q. (2024). Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma. Molecular Cell, 84(4):776-790.
[3]. Zhu, X., Zhang, H., Mendell, JT. (2020). Ribosome recycling by ABCE1 links lysosomal function and iron homeostasis to 3ʹ UTR-directed regulation and nonsense-mediated decay. Cell Reports, 32(2):107895.
[4]. Zhu, X., Xie, S., Xu, T., Wu, X., and Han, M. (2017). Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders. Molecular Metabolism, 6(6):494-502.
[5]. Cui, J., Ding, Y., Chen, S., Zhu, X., Wu, Y., Zhang, M., Zhao, Y., Li, TR., Sun, LV., Zhao, S., Zhuang, Y., Jia, W., Xue, L., Han, M., Xu, T., Wu, X. (2016). Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity. The Journal of Clinical Investigation, 126(9):3192-206.
[6]. Lei, K., Zhu, X., Xu, R., Shao, C., Xu, T., Zhuang, Y., and Han, M. (2012). Inner Nuclear Envelope Proteins SUN1 and SUN2 Play a Prominent Role in the DNA Damage Response. Current Biology, 22(17):1609–1615.
[7]. Morimoto, M., Shibuya, H., Zhu, X., Kim, J., Ishiguro, K., Han, M., and Watanabe, Y. (2012). A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis. The Journal of Cell Biology, 198(2):165–172.