南京市栖霞区仙林大道163号，210023
xuemei.yang@nju.edu.cn
15190400637工作经历
2022-2023，香港城市大学博士后
2023-2025，香港理工大学博士后
2025-，南京大学 特聘研究员/准聘副教授、博导
荣誉奖励
2024，国家级青年人才计划
2025，教育部科学研究优秀成果奖二等奖（排名4）
学术任职
代表性成果
1. Wang, J.#, Yang, X.#, Huang, Z.#, Su, Y., Zhang, X., Song, N., Wang, P., Yang, C., Cao, H., Liu, X.-W., Li, X.*, Chen, S.* & Li, M.* (2025). Synthesis of Campylobacter jejuni capsular oligosaccharides and identification of a potential O-antigen against campylobacteriosis. Science Advances.11(15), eadu2318.
2. Yang, X., Zhang, H., Tang, Y., Heng, H., Cheung, YC., Song, X., Kong, HK., Chan, E. W.-C., Zhang, R. & Chen, S.* (2024). Functional relay between Mph(A) enzyme and Mrx efflux pump mediates azithromycin resistance, a novel mechanism of bacterial antimicrobial resistance. Drug Resistance Updates. 77, 101127.
3. Yang, X., Wei, R., Liu, H., Wei, T., Zeng, P., Cheung, Y. C., Heng, H., Chan, E. W., Li, X.* & Chen, S.* (2024). Discovery of a monoclonal antibody that targets cell-surface Pseudaminic acid of Acinetobacter baumannii with direct bactericidal effect. ACS Central Science. 10(2), 439-446.
4. Yang, X., Man, M.-Y., Heng, H., Chan, B. K.-W., Hu, Q., Chan, E. W.-C., Shum, H.-P.* & Chen, S.* (2024). Molecular epidemiology and clinical impact of Klebsiella spp. causing bloodstream infections in Hong Kong. EBioMedicine. 101, 104998.
5. Yang, X., Zhang, H., Chan, E. W.-C., Zhang, R. & Chen, S.* (2024). Transmission of azithromycin-resistant gene, erm(T), of Gram-positive bacteria origin to Klebsiella pneumoniae. Microbiological Research. 282, 127636.
6. Yang, X., Sun, Q., Li, J., Jiang, Y., Li, Y., Lin, J., Chen, K., Chan, E. W-C., Zhang, R.*, & Chen, S.* (2022). Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China. Emerging Microbes and Infections. 11(1), 841-849.
7. Yang, X., Liu, X., Xu, Y., Chan, E. W., Zhang, R. & Chen, S.* (2022). An IncB/O/K/Z conjugative plasmid encodes resistance to azithromycin and mediates transmission of virulence plasmid in Klebsiella pneumoniae. International Journal of Antimicrobial Agents. 60, 5-6, 106683.
8. Yang, X., Xie, M., Xu, Q., Ye, L., Yang, C., Dong, N., Chan, E. W-C., Zhang, R., & Chen, S.* (2022). Transmission of pLVPK-like virulence plasmid in Klebsiella pneumoniae mediated by an Incl1 conjugative helper plasmid. iScience. 25(6), 104428.
9.Yang, X., Ye, L., Chan, E. W-C., Zhang, R., & Chen, S.* (2021). Characterization of an IncFIB/IncHI1B plasmid encoding efflux pump TMexCD1-TOprJ1 in a clinical tigecycline- and carbapenem-resistant Klebsiella pneumoniae strain. Antimicrobial Agents and Chemotherapy. 65(4), e02340-20.
10. Yang, X., Dong, N., Chan, E. W-C., Zhang, R., & Chen, S.* (2021). Carbapenem Resistance-Encoding and Virulence-Encoding Conjugative Plasmids in Klebsiella pneumoniae. Trends in Microbiology. 29(1), 65-83.
11. Wei, R.#, Yang, X.#, Liu, H., Wei, T., Chen, S.,* & Li, X.* (2021). Synthetic Pseudaminic-acid-based antibacterial vaccine confers effective protection against Acinetobacter baumannii infection. ACS Central Science. 7(9), 1535-1542.
12. Yang, X.#, Dong, N.#, Chan, E. W-C., & Chen, S.* (2020). Genetic cluster analysis of SARS-CoV-2 and the identification of those responsible for the major outbreaks in various countries. Emerging Microbes and Infections. 9(1), 1287-1299.
13. Yang, X., Ye, L., Chan, E. W-C., Zhang, R., & Chen, S.* (2020). Tracking recombination events that occur in conjugative virulence plasmid p15WZ-82_Vir during the transmission process. mSystems. 5(4), e00140-20.
14. Yang, X., Ye, L., Li, Y., Chan, E. W-C., Zhang, R.*, & Chen, S.* (2020). Identification of a chromosomal integrated DNA fragment containing the rmpA2 and iucABCDiutA virulence genes in Klebsiella pneumoniae. mSphere. 5(6), e01179-20.
15. Yang, X., Chan, E. W-C., Zhang, R., & Chen, S.* (2019). A conjugative plasmid that augments virulence in Klebsiella pneumoniae. Nature Microbiology. 4(12), 2039-2043.