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张玉婧
副教授
研究领域
分泌miRNA的功能与应用
南京市栖霞区仙林大道163号,210023
yjzhang@nju.edu.cn

工作经历

2011-2016,南京大学生命科学学院,助理研究员

2016至今,南京大学生命科学学院,副教授


荣誉奖励


学术任职

2022-,《Frontiers In Immunology》(IF:8.9) 客作编辑


代表性成果

[1] Jing Li#, Yujing Zhang#, Yangyang Ye#, Dameng Li#, Yuchen Liu, Eunyoung Lee, Mingliang Zhang, Xin Dai, Xiang Zhang, ShibeiWang, Junfeng Zhang, Weiping Jia, Ke Zen*, Antonio Vidal-Puig*, Xiaohong Jiang*,  Chen-Yu Zhang*, Pancreatic β cells control glucose homeostasis via the secretion of exosomal miR-29 family. J Extracell Vesicles, 2021 Jan;10(3):e12055.

[2] Dameng Li#, Huichen Song1#, Linghu Shuo, Lei Wang, Ping Xie, Weili Li, Jiachen Liu, Yafei Tong, Chen-Yu Zhang, Xiaohong Jiang*, Jing Li*, Yujing Zhang*,Gonadal white adipose tissue-derived exosomal MiR-222 promotes obesity-associated insulin resistance. Aging-US, 2020 Nov 10;12(22):22719-22743

[3] Zheng S, Guo S, Sun G, Shi Y, Wei Z, Tang Y, He F, Shi C, Dai P, Chong H, Samuelson I, Zen K, Zhang CY, Zhang Y*, Li J*, Jiang X*. Gain of Metabolic Benefit with Ablation of miR-149-3p from Subcutaneous Adipose Tissue in Diet-Induced Obese Mice. Mol Ther Nucleic Acids. 2019 Aug 26;18:194-203.

[4] Zhang A#, Li D#, Liu Y, Li J, Zhang Y*, Zhang CY*, Islet β cell: An endocrine cell secreting miRNAs, Biochem Biophys Res Commun. 2018 Jan 8;495(2):1648-1654

[5] Liu Y, Li D, Liu Z, Zhou Y, Chu D, Li X, Jiang X, Hou D, Chen X, Chen Y, Yang Z, Jin L, Jiang W, Tian C, Zhou G,Zen K, Zhang J, Zhang Y*, Li J*, Zhang CY*. Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse. Sci Rep. 2015 Dec 3;5:17543. doi: 10.1038/srep17543

[6] Li J+, Zhang Y+, Li D, Liu Y, Chu D, Jiang X, Hou D, Zen K, Zhang CY. Small noncoding RNAs transfer through mammalian placenta and directly regulate fetal gene expression. Protein Cell. 2015 Jun;6(6):391-6. Doi:10.1007/s13238-015-0156-2. 

[7] Zhang J, Li L, Li J, Liu Y, Zhang CY*, Zhang Y*, Zen K*. Protein tyrosine phosphatase 1B impairs diabetic wound healing through vascular endothelial growth factor receptor 2 dephosphorylation. (2015) Arterioscler Thromb Vasc Biol.Jan;35(1):163-74.

[8] Liu Y, Zhao L, Li D, Yin Y, Zhang CY*, Li J*, Zhang Y*. Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF, and the neutralization of miR-150 attenuate tumor development. (2013) Protein & Cell. 4(12):932-941. 

[9] Li J+, Zhang Y+, Liu Y, Dai X, Li W, Cai X, Yin Y, Wang Q, Xue Y, Wang C, Li D, Hou D, Jiang X, Zhang J, Zen K*, Chen X*, Zhang CY*. Microvesicle-mediated transfer of miR-150 from monocytes to endothelial cells promotes angiogenesis. (2013) The Journal of Biological Chemistry. 2013 Aug 9;288(32):23586-96. 

[10] Zhang Y+, Liu D+, Chen X+, Li J, Li L, Bian Z, Sun F, Lu J, Yin Y, Cai X, Sun Q, Wang K, Ba Y, Wang Q, Wang D, Yang J, Liu P, Xu T, Yan Q, Zhang J*, Zen K*, Zhang CY*. Secreted monocytic miR-150 enhances targeted endothelial cell migration. (2010) Mol Cell 39(1): 133-144.