江苏省南京市栖霞区仙林大道163号
xijuanliu@nju.edu.cn
18761660634工作经历
2017.9 –2022.9美国北卡罗莱纳大学教堂山分校博士后
2022.10-2023.2 美国北卡罗莱纳大学教堂山分校Research Associate
2023.6至今 南京大学现代生物研究院研究员、课题组长、博导
荣誉奖励
国家高层次优秀青年项目（海外）, 2024-2027
学术任职
美洲华人生物科学学会，会员
代表性成果
1. Xijuan Liu#, Wang J#, Gong W, Zhao S, Zhang C, Wu Q, Jain K, Boyer JA, Guo Y, Rodriguez J, Li M, Uryu H, Liao C, Hu L, Zhou J, Shi X, Tsai YH, Yan Q, Luo W, Zhang Q, Strahl BD, Kriegsheim A, Wang GG*, Baldwin AS*, Zhang Q*. 2022. Histone H3 proline 16 hydroxylation regulates mammalian gene expression. Nature Genetics, 2022, https://doi.org/10.1038/s41588-022-01212-x. News & Views by Nature Genetics.
2. Xijuan Liu, Simon JM, Xie H, Hu L, Wang J, Zurlo G, Fan C, Ptacek TS, Herring L, Tan X, Li M, Baldwin AS, Kim WY, Wu T, Kirschner MW, Gong K, Zhang Q. 2020. Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss. Mol Cell 77:1294-1306 e5.
3. Xie H#, Zhou J#, Xijuan Liu#, Xu Y, Simon JM, Hepperla A, Liao C, Baldwin AS, Gong K*, Zhang Q*. USP13 Promotes Deubiquitination of ZHX2 and Tumorigenesis in Kidney Cancer. 2022, Proc Natl Acad Sci U S A 119 (36) e2119854119.
4. Xijuan Liu, Zurlo G, Zhang Q. 2020. The Roles of Cullin-2 E3 Ubiquitin Ligase Complex in Cancer. Adv Exp Med Biol 1217:173-186. (Chapter)
5. Jun Wang#, Xijuan Liu#, David F. Allison, Aaron J. Storey, Dongxu Li, Weida Gong, Stephanie
D. Byrum, Yi-Hsuan Tsai, Jeong Hyun Ahn, Rick D. Edmondson, Cheng Fan, Samuel G. Mackintosh, Jesse R. Raab, Alan J. Tackett, Charles M. Perou, Ling Cai*, Gang Greg Wang*(co- first author, manuscript, will submit soon)
6. Chengheng Liao#, Xijuan Liu#, Cheng Zhang#, Qing Zhang *. Tumor hypoxia: From basic knowledge to therapeutic implications.(Seminars in Cancer Biology, 2022, revision, review).
7. Xijuan Liu, Yang B, Huang SN, Wu CC, Li XJ, Cheng S, Jiang X, Hu F, Ming YZ, Nevels M, Britt WJ, Rayner S, Tang Q, Zeng WB, Zhao F, Luo MH. 2017. Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase. PLoS Pathog 13:e1006542.
8. Xijuan Liu, Xuan Jiang, Sheng-Nan Huang, Jin-Yan Sun,Fei zhao ,Wen-Bo Zeng, Min-Hua Luo (2017). Human Cytomegalovirus Infection Dysregulates Neural Progenitor Cell Fate by Disrupting Hes1 Rhythm and Down-regulating Its Expression. VIROLOGICA SINICA, 2017 Jun; 32(3): 188–198. PMID: 2845189